Key Takeaways
- Most side effects are gastrointestinal
- Common during dose escalation
- Often temporary and manageable
Detailed Explanation
Common (very frequent)
- Nausea
- Diarrhoea
- Constipation
- Reduced appetite
Less Common
- Vomiting
- Indigestion
- Fatigue
Rare but Serious
- Severe abdominal pain (possible pancreatitis)
- Persistent vomiting or dehydration
- Signs of allergic reaction (rash, swelling, breathing difficulty)
Why Side Effects Occur
Mounjaro works on GLP-1 and GIP receptors, which:
- Slow gastric emptying
- Reduce appetite
- Affect gut signalling
This is why most side effects are digestive.
What You Should Do
- Continue treatment if symptoms are mild
- Eat smaller meals and avoid fatty foods
- Stay hydrated
When to Seek Help
- Severe or persistent abdominal pain
- Ongoing vomiting
- Signs of dehydration or allergic reaction